Retatrutide is a weight loss medication that works through several mechanisms to help individuals lose weight. While the exact details of its action may involve complex physiological processes, its primary modes of action can be summarized as follows:

Appetite Suppression: Retatrutide is believed to influence the appetite-regulating centers in the brain, specifically targeting the hypothalamus. By modulating certain neuropeptides and neurotransmitters, it can reduce feelings of hunger and increase feelings of satiety. This appetite-suppressing effect can lead to a decrease in calorie intake, which is essential for weight loss.